What’s the Difference Between Juvederm vs. Restylane vs. Versa vs. Belotero vs. RHA: The Ultimate Dermal Filler Guide for Austin


  • Based on research data, all five FDA-approved hyaluronic acid based dermal fillers (Restylane, Juvederm, Belotero, RHA and Versa) are effective and well-tolerated.
  • Versa has a different manufacturing process that removes impurities and reduces adverse events and a lower price for medical practices from the manufacturer.
  • Belotero has a lower G prime (softer and flexible), which is perfect for lips.

In the world of cosmetic enhancements, dermal fillers stand out as a popular choice for patients looking to diminish the signs of aging and achieve a more youthful, radiant complexion. With a variety of options available, it can be challenging to navigate the differences between each type of filler and determine which one is right for you. Let’s dive into the world of dermal fillers, exploring Juvederm, Restylane, RHA, Versa, and Belotero, to help you make an informed decision.

What is Juvederm?

Juvederm is a family of hyaluronic acid (HA) fillers designed to address various areas of the face. Known for its smooth consistency, Juvederm effectively plumps up lips, smooths lines around the mouth, and restores volume to cheeks. Its formulation is based on Hylacross technology, providing long-lasting results and a natural feel.

The family of Juverderm fillers include the following:

JUVEDERM: FDA approved in 2008, Juvederm is a family of fillers manufactured by Allergan made with Hylacross technology.

JUVEDERM XC: XC initials indicates that lidocaine is added to the HA

JUVEDERM ULTRA PLUS: thicker HA for correction of facial wrinkles and folds (Hylacross)

JUVEDERM VOLUMA: HA for deeper injection in the cheek and chin made with Vycross technology.

JUVEDERM VOLBELLA: use for lips and under eye (Vycross)

JUVEDERM VOLLURE: use for moderate to severe facial wrinkles (Vycross)

What is Restylane?

Restylane, another HA-based filler, was the first of its kind to receive FDA approval in the USA. Utilizing NASHA technology, Restylane offers a slightly firmer texture, making it ideal for sculpting and defining facial features. It’s particularly effective in enhancing lips, filling nasolabial folds, and rejuvenating the under-eye area.

The family of Restylane fillers include the following:

Restylane: The first FDA approved HA dermal filler in the USA in 2003. Restylane has a family of fillers manufactured by Galderma. This is the original HA filler made with NASHA technology.

RESTYLANE-L: original HA filler with lidocaine

RESTYLANE LYFT: formally called Perlane, this is used in the cheeks (NASHA)

RESTYLANE SILK: used in lips (NASHA) 

RESTYLANE DEFYNE: made with new XpresHAn Technology for deeper nasolabial fold, marionette lines and chin

RESTYLANE REFYNE: made with new XpresHAn Technology for nasolabial fold and marionette lines

RESTYLANE KYSSE: made with new XpresHAn Technology for lips

What is RHA?

RHA, or Resilient Hyaluronic Acid, represents the latest advancement in HA filler technology. Designed to mimic the natural HA found in the skin, RHA fillers are uniquely formulated to adapt to the dynamic movements of the face, providing a more natural-looking result during facial expressions.

The family of RHA fillers include the following:

RHA Redensity: Fine-tuned finish for moderate to severe dynamic perioral rhytids. A softer, finer filler for superficial filling like smoker’s lines. 

RHA 2: Elegant softening for dynamic lines and moderate to severe volume deficits.

RHA 3: Refined smoothing for moderate to severe dynamic wrinkles and folds. A moderately robust filler for areas like marionette lines and smile lines. 

RHA 4: Natural volume for moderate to severe dynamic folds and deeper deficits. A thicker formulation for a deeper implantation.

What is Versa?

Versa is a versatile HA filler known for its homogenous particle size, thanks to a proprietary manufacturing process. This uniformity allows for smoother injections and potentially less swelling post-treatment. Versa is celebrated for its ability to correct moderate to severe facial wrinkles and folds with precision.

REVANESSE VERSA: FDA approved in 2017, Versa is manufactured by Prollenium and is used for the correction of moderate-to-severe facial wrinkles and folds, such as nasolabial folds. Versa is manufactured using a special proprietary method to ensure that the HA spheres are all perfectly rounded and are exactly the same size.

REVANESSE LIPS+:  FDA approved in 2020, Lips+ is manufactured by Prollenium and is used for the correction of lips.

What is Belotero?

Belotero is an HA filler that integrates seamlessly into the skin, offering a smooth transition between treated and untreated areas. It’s particularly adept at treating fine lines and more superficial wrinkles, thanks to its unique Cohesive Polydensified Matrix (CPM) technology.

BELOTERO: FDA approved in 2011, Belotero is manufactured by Merz and is used for the correction of moderate-to-severe facial wrinkles and folds, such as nasolabial folds.

What’s The Difference?

While all these fillers are HA-based, their differences lie in their formulation, texture, and recommended areas of use. Juvederm and Restylane offer a range of products tailored to specific concerns, RHA excels in natural-looking dynamic results, Versa provides uniformity and potentially less swelling, and Belotero specializes in treating fine lines with seamless integration.

How long do they last?

The longevity of these fillers can vary: Juvederm and Restylane products typically last between 6 to 12 months, RHA fillers maintain their effect for up to 12 months, Versa results can last for about 12 months, and Belotero effects are visible for about 6 to 12 months. However, in our experience, the majority of the patients will have effects from 3 to 6 months depending on the area injected.

Are there differences in concentration?

Yes, each filler has a different HA concentration, affecting its viscosity, elasticity, and ideal placement depth. Higher concentrations are generally used for deeper folds and volume restoration, while lower concentrations are suited for fine lines and superficial placement. 

Are there any differences with the procedures?

The injection techniques may vary slightly depending on the filler’s consistency and the area being treated. However, all procedures involve minimally invasive injections performed by a skilled practitioner.

Are there any differences in the effectiveness?

Effectiveness is often subjective and based on individual patient needs and expectations. All fillers are effective in their recommended applications, but personal preference and specific aesthetic goals can influence the choice of filler.

Side effects

Common side effects include temporary redness, swelling, bruising, and tenderness at the injection site. These are generally mild and resolve quickly. Serious side effects are rare but can include allergic reactions or filler migration.

Deciding Between Dermal Fillers for You

Choosing the right dermal filler involves considering your specific aesthetic goals, the areas you wish to treat, and discussing your options with our qualified medical professional. Whether you’re looking for volume restoration, fine line smoothing, or natural-looking results that move with your facial expressions, there’s a filler that can meet your needs.

Selecting the perfect place for your dermal filler treatments is crucial, and Medspa of Austin stands out as the ideal choice. We’re proud to offer many types of dermal fillers, ensuring a broad array of options that are customized just for you. In our reviews, patients tell us that we are the best medspa near you in Austin because we’re dedicated to designing personalized treatment with your desires and price in mind. 

Book online for your FREE CONSULTATION to find out which is right for you.

Contact us at (737) 386-4306 or email@medspaofaustin.com today!

Disclaimer: Results may vary from person to person. Consult with our medical injectors to determine the best treatment for your specific needs.